Researchers are always searching for ways to modulate hormone levels and metabolism in the quest to find cures for breast, prostate, ovarian, and other cancers that afflict the
reproductive organs. Hormone-dependent cancers are usually more aggressive and difficult to treat. A research team from the Strang Cancer Research Laboratory at Hackensack University
presented a study in San Antonio that found that extracts of goji inhibited a specific pathway of estrogen metabolism that is known to encourage the growth of hormone-dependent breast
cancers.
More specifically, women with breast cancer usually have accelerated C16-alpha hydroxylation of the estrogen in their bodies. This is a method the body uses to break down extra or
"used-up" estrogen, but it yields a product called 17 beta-estradiol, also known as E2's8212;a known promoter of breast cancer growth.
In a test tube-study, the investigators demonstrated that goji caused human breast cancer cells to down-regulate this pathway of estrogen metabolism.
This is huge news, and yet another reason to get your goji!
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REFERENCES
Telang NT, et al, "Chinese herb lycium barbarum inhibits growth of hormone responsive human breast cancer cells by down-regulating C16-hydroxylation pathway of estradiol metabolism,"
presented at 2005 San Antonio Breast Cancer Symposium in San Antonio, TX.