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FLAVORx Develops Formulary for Medication Linked to Prevention of Diabetes

Researchers recently reported that Avandia, a widely-prescribed drug in the treatment of diabetes, may also play a key role in prevention of the disease. The study involved over 5,000 people with a 's8220;pre-diabetes's8221; condition and abnormal blood sugar levels in 21 countries over a 3-year period. Participants who took Avandia reduced their risk of developing diabetes or dying by over 50%. In light of this information, FLAVORx has recently developed a safe and effective formulary for flavoring this medication to provide better patient services for children affected by type 2 diabetes.



The secondary portion of the study utilized the blood pressure drug Altace, and no difference in the risk of developing diabetes in patients was found. These results conclude that Avandia did indeed influence prevention and was not simply an anomaly in calculation. The risk reduction reported with Avandia was double that reported with any other drug used in diabetes prevention.



FLAVORx's8217;s formulary for Avandia utilizes scientifically-designed flavorings in combination with both a proprietary Bitterness Suppressor and proprietary Sweetening Enhancer. The FLAVORx Sweetening Enhancer is 100x sweeter than table sugar, yet is sugar-free and does not contain aspartame. The make-up of the Sweetening Enhancer is therefore completely safe for children with diabetes or phenylketonuria (PKU). The formulation converts Avandia tablets to suspension, which can then be easily flavored for patients, such as young children, who have difficulty swallowing pills. By utilizing the FLAVORx system to improve the taste, smell and overall palatability of a medication, children will no longer struggle with bitter or foul medications, and thereby be more willing to follow and complete comprehensive drug treatment programs. FLAVORx has recommended the flavors such as Grape, Raspberry and Watermelon to pharmacists nationwide as the flavors most successful at masking Avandia's8217;s existing taste.    




According to Kenny Kramm, FLAVORx President and CEO, 's8220;This is phenomenal breakthrough in diabetes research and we are thrilled to have developed a safe formulation for this drug. Not only are we able to improve patient care programs, but now we can also contribute to the potential prevention of the disease.'s8221;



It is estimated that 20.8 million children and adults are afflicted with diabetes in the US. However, studies indicate that nearly 1/3 of these individuals, roughly 6 million people, are unaware that they have diabetes, making diagnosis all the more pertinent for those who feel they may exhibit classic diabetes symptoms. Common symptoms include frequent urination, excessive thirst, extreme hunger, unusual weight loss, irritability, increased fatigue and blurry vision. Detection of these symptoms early on may lead to the diagnosis of 's8216;pre-diabetes,'s8217; a condition that indicates high blood glucose levels not yet high enough to be considered diabetes.According to the American Diabetes Association, 54 million people in the US are living with pre-diabetes. Research indicates that if patients are able to manage blood glucose levels during this pre-diabetes period with medications like Avandia, they may be able to delay or prevent the progression to type 2 diabetes. This means that in the best case scenario, potentially 54 million people, or approximately 6% of the entire US population may be able to prevent the development of diabetes and thus more serious complications such as cardiovascular problems and even death.



In children and young adults, type 1 diabetes is most common; however it appears that in recent years the number of type 2 diabetes cases in children has increased significantly. Researchers link this rise to factors such as puberty, which may affect hormone levels and the body's8217;s processing of insulin, and also childhood obesity, which may cause the excessive production of insulin. Experts recommend education, meal planning, physical exercise and the proper use of medications and insulin therapy to treat diabetes in children.



For the past 17 years, Mary Tyler Moore has been the international chairperson of the Juvenile Diabetes Research Foundation (JDRF). Moore was diagnosed with Type 1 diabetes over 30 years ago and has since undergone multiple procedures to combat the complications of her disease. As an active supporter in the mission to eliminate the suffering of young children with diabetes and an advocate of the nation'ss responsibility to find a cure, Moore notes, Each child faces a future with the risk of early blindness, kidney failure, amputation, heart attack, and stroke.



FLAVORx is available in over 35,000 pharmacies nationwide such as Walgreens, CVS, Rite-Aid and Wal-Mart. FLAVORx flavors are non-allergenic, sugar-free, dye-free, alcohol-free, phosphate-free and extremely concentrated so that only a small amount is used for even large volumes of medication. For more information, please contact Teresa Chen at 800.884.5771 extension 234.

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