Particle Sorting Demonstrated in a Custom Flowcell with Integrated Electrodes



Intelligent discrimination of target particles of interest from a complex liquid matrix is of critical interest in biodefense and homeland security applications. A miniaturized system for dielectrophoresis (DEP) based particle and cell sorting is being developed by CFD Research Corporation (CFDRC), Huntsville, AL.

Important for the realization of miniaturized and multiplexed systems is the requirement for laminar flow and the movement of particles/cells in response to an electric field. Such a system requires the use of micron-sized flow channels with a very small electrode gap (10 - 50 microns) to obtain the electric field strengths necessary to effect particle sorting at nominal values of the applied

voltage.

To achieve the design requirements, ALine (



Particle Sorting Demonstrated in a Custom Flowcell with Integrated Electrodes